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MolNFT v1 · #241526 · protein

AlphaFold monomer V2.0 prediction for myelin-oligodendrocyte glycoprotein (Q63345)

Q63345: “AlphaFold monomer V2.0 prediction for myelin-oligodendrocyte glycoprotein (Q63345)”. 1 pocket (best druggability 0.33). MolNFT v1 #241526 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession
Q63345
Type
protein
Length
245 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x40B9C9d5F084D34d026E9d5Dd10501AcdF6d6152
Molecule
Myelin-oligodendrocyte glycoprotein
UniProt
Q63345
Pockets
1 · best druggability 0.33

Structure

1 distinct chain · 42% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMyelin-oligodendrocyte glycoproteinprotein24542% helix, 25% strandQ63345

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1890.330.7320empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 1PKQ · Myelin oligodendrocyte glycoprotein-(8-18C5) Fab-complex · an experimental structure of the same protein · chain A against E, TM-score 0.49
  • 1PKQ · Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex · an experimental structure of the same protein · chain A against E, TM-score 0.49
  • 1PKO · Myelin Oligodendrocyte Glycoprotein (MOG) · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 1PKO · Myelin oligodendrocyte glycoprotein (mog) · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 3CSP · Crystal structure of the DM2 mutant of myelin oligodendrocyte glycoprotein · an experimental structure of the same protein · chain A against A, TM-score 0.49
  • 3CSP · Crystal structure of the DM2 mutant of myelin oligodendrocyte glycoprotein · an experimental structure of the same protein · chain A against A, TM-score 0.49

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