MolNFT v1 · #236335 · protein
AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 9 (P49186)
P49186: “AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 9 (P49186)”. 5 pockets (best druggability 0.71). MolNFT v1 #236335 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P49186
- Type
- protein
- Length
- 423 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xef9501Aaf0616406baEf54cf5Eb203106Fef9739
- Molecule
- Mitogen-activated protein kinase 9
- UniProt
- P49186
- Pockets
- 5 · best druggability 0.71
Structure
1 distinct chain · 35% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen-activated protein kinase 9 | protein | 423 | 35% helix, 14% strand | P49186 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 571 | 0.71 | 0.79 | 55 | empty |
| 2 | 297 | 0.57 | 0.77 | 36 | empty |
| 3 | 125 | 0.47 | 0.78 | 24 | empty |
| 4 | 65 | 0.34 | 0.76 | 14 | empty |
| 5 | 62 | 0.30 | 0.74 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49186
- Elsewhere: UniProt P49186 · AlphaFold DB P49186
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