MolNFT v1 · #226863 · protein
AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 13-like (A2VCZ5)
A2VCZ5: “AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 13-like (A2VCZ5)”. 20 pockets (best druggability 0.85). MolNFT v1 #226863 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- A2VCZ5
- Type
- protein
- Length
- 2,102 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc4D46881AFD81F838F24Bb4F822bcC9938d48395
- Molecule
- Mediator of RNA polymerase II transcription subunit 13-like
- UniProt
- A2VCZ5
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 21% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 13-like | protein | 2102 | 21% helix, 11% strand | A2VCZ5 |
Pockets
20 pockets found on a 1 Å grid, 13 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 969 | 0.85 | 0.86 | 117 | empty |
| 2 | 514 | 0.82 | 0.89 | 54 | empty |
| 3 | 1035 | 0.78 | 0.80 | 115 | empty |
| 4 | 68 | 0.73 | 0.97 | 18 | empty |
| 5 | 870 | 0.71 | 0.76 | 65 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A2VCZ5
- Elsewhere: UniProt A2VCZ5 · AlphaFold DB A2VCZ5
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