MolNFT v1 · #199412 · protein

AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 8 (Q15842)

Q15842: “AlphaFold monomer V2.0 prediction for ATP-sensitive inward rectifier potassium channel 8 (Q15842)”. 3 pockets (best druggability 0.47). MolNFT v1 #199412 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q15842
Type: protein
Length: 424 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule: ATP-sensitive inward rectifier potassium channel 8
UniProt: Q15842
Pockets: 3 · best druggability 0.47

Structure

1 distinct chain · 39% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ATP-sensitive inward rectifier potassium channel 8	protein	424	39% helix, 21% strand	Q15842

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	140	0.47	0.77	22	empty
2	234	0.47	0.73	33	empty
3	53	0.30	0.76	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q15842
Elsewhere: UniProt Q15842 · AlphaFold DB Q15842

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