MolNFT v1 · #191446 · protein
AlphaFold monomer V2.0 prediction for spindle assembly checkpoint kinase (Q6BVA0)
Q6BVA0: “AlphaFold monomer V2.0 prediction for spindle assembly checkpoint kinase (Q6BVA0)”. 6 pockets (best druggability 0.76). MolNFT v1 #191446 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q6BVA0
- Type
- protein
- Length
- 412 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x3298b100681D3A2372Bba3b2f282750dD71629B9
- Molecule
- Spindle assembly checkpoint kinase
- UniProt
- Q6BVA0
- Pockets
- 6 · best druggability 0.76
Structure
1 distinct chain · 38% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spindle assembly checkpoint kinase | protein | 412 | 38% helix, 13% strand | Q6BVA0 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 543 | 0.76 | 0.83 | 47 | empty |
| 2 | 489 | 0.69 | 0.79 | 36 | empty |
| 3 | 255 | 0.52 | 0.75 | 36 | empty |
| 4 | 118 | 0.49 | 0.80 | 21 | empty |
| 5 | 72 | 0.33 | 0.75 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6BVA0
- Elsewhere: UniProt Q6BVA0 · AlphaFold DB Q6BVA0
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