MolNFT v1 · #190476 · protein
AlphaFold monomer V2.0 prediction for insulin receptor-related protein (P14617)
P14617: “AlphaFold monomer V2.0 prediction for insulin receptor-related protein (P14617)”. 16 pockets (best druggability 0.71). MolNFT v1 #190476 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P14617
- Type
- protein
- Length
- 1,300 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7782F4817b37743d738e9aF842bf74bd50f2015E
- Molecule
- Insulin receptor-related protein
- UniProt
- P14617
- Pockets
- 16 · best druggability 0.71
Structure
1 distinct chain · 17% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Insulin receptor-related protein | protein | 1300 | 17% helix, 26% strand | P14617 |
Pockets
16 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 858 | 0.71 | 0.76 | 74 | empty |
| 2 | 256 | 0.71 | 0.86 | 37 | empty |
| 3 | 373 | 0.58 | 0.76 | 33 | empty |
| 4 | 142 | 0.53 | 0.81 | 29 | empty |
| 5 | 150 | 0.52 | 0.80 | 25 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P14617
- Elsewhere: UniProt P14617 · AlphaFold DB P14617
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