MolNFT v1 · #186805 · protein
AlphaFold monomer V2.0 prediction for insulin-like growth factor 1 receptor (P24062)
P24062: “AlphaFold monomer V2.0 prediction for insulin-like growth factor 1 receptor (P24062)”. 13 pockets (best druggability 0.73). MolNFT v1 #186805 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P24062
- Type
- protein
- Length
- 1,370 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x1FdF165eB42e29a6686Ef2Ac96F71Aab73034EDE
- Molecule
- Insulin-like growth factor 1 receptor
- UniProt
- P24062
- Pockets
- 13 · best druggability 0.73
Structure
1 distinct chain · 18% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Insulin-like growth factor 1 receptor | protein | 1370 | 18% helix, 25% strand | P24062 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.73 | 0.87 | 30 | empty |
| 2 | 578 | 0.65 | 0.76 | 51 | empty |
| 3 | 418 | 0.60 | 0.76 | 44 | empty |
| 4 | 233 | 0.58 | 0.79 | 36 | empty |
| 5 | 176 | 0.54 | 0.80 | 28 | empty |
Modifications
Observed in the structure: 17 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P24062
- Elsewhere: UniProt P24062 · AlphaFold DB P24062
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