MolNFT v1 · #152638 · protein

AlphaFold monomer V2.0 prediction for monothiol glutaredoxin-3 (Q03835)

Q03835: “AlphaFold monomer V2.0 prediction for monothiol glutaredoxin-3 (Q03835)”. 1 pocket (best druggability 0.63). MolNFT v1 #152638 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

Accession: Q03835
Type: protein
Length: 250 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xd27f4D98eE625C1f8E81f7ac0eF38f876f24543e
Molecule: Monothiol glutaredoxin-3
UniProt: Q03835
Pockets: 1 · best druggability 0.63

Structure

1 distinct chain · 39% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Monothiol glutaredoxin-3	protein	250	39% helix, 19% strand	Q03835

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	204	0.63	0.83	43	empty

Compared structures

3D6I · Structure of the Thioredoxin-like Domain of Yeast Glutaredoxin 3 · an experimental structure of the same protein · chain A against A, TM-score 0.43
3D6I · Structure of the thioredoxin-like domain of yeast glutaredoxin 3 · an experimental structure of the same protein · chain A against A, TM-score 0.43
5Y4U · Crystal structure of grx domain of GRX3 from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.39
5Y4U · Crystal structure of Grx domain of Grx3 from Saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.39

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q03835
Elsewhere: UniProt Q03835 · AlphaFold DB Q03835

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