MolNFT v1 · #129959 · protein
AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 3 (O42127)
O42127: “AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 3 (O42127)”. 8 pockets (best druggability 0.70). MolNFT v1 #129959 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- O42127
- Type
- protein
- Length
- 802 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x2a7AdD564c0554f2678aF0B7b36468EdBbF1e6D5
- Molecule
- Fibroblast growth factor receptor 3
- UniProt
- O42127
- Pockets
- 8 · best druggability 0.70
Structure
1 distinct chain · 19% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fibroblast growth factor receptor 3 | protein | 802 | 19% helix, 26% strand | O42127 |
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 503 | 0.70 | 0.80 | 47 | empty |
| 2 | 251 | 0.60 | 0.80 | 34 | empty |
| 3 | 208 | 0.50 | 0.76 | 22 | empty |
| 4 | 118 | 0.38 | 0.74 | 17 | empty |
| 5 | 88 | 0.34 | 0.74 | 19 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O42127
- Elsewhere: UniProt O42127 · AlphaFold DB O42127
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