MolNFT v1 · #129944 · protein
AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 1 (P22182)
P22182: “AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 1 (P22182)”. 8 pockets (best druggability 0.72). MolNFT v1 #129944 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- P22182
- Type
- protein
- Length
- 812 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd91633319BDB0a92cbC4f08DeA734Bf74C030064
- Molecule
- Fibroblast growth factor receptor 1
- UniProt
- P22182
- Pockets
- 8 · best druggability 0.72
Structure
1 distinct chain · 20% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fibroblast growth factor receptor 1 | protein | 812 | 20% helix, 26% strand | P22182 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 547 | 0.72 | 0.81 | 60 | empty |
| 2 | 524 | 0.62 | 0.75 | 42 | empty |
| 3 | 296 | 0.59 | 0.78 | 51 | empty |
| 4 | 209 | 0.56 | 0.79 | 27 | empty |
| 5 | 299 | 0.53 | 0.75 | 36 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22182
- Elsewhere: UniProt P22182 · AlphaFold DB P22182
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