AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase, H3 lysine-79 specific (Q8TEK3)

Structure

1 distinct chain.

Compared structures

• 3UWP · Crystal structure of DOT1L in complex with 5-iodotubercidin · an experimental structure of the same protein · chain A against A, TM-score 0.22
• 3UWP · Crystal structure of Dot1l in complex with 5-iodotubercidin · an experimental structure of the same protein · chain A against A, TM-score 0.22
• 4WVL · Structure-guided DOT1L probe optimization by label-free ligand displacement · an experimental structure of the same protein · chain A against A, TM-score 0.21
• 4ER6 · Crystal structure of human DOT1L in complex with inhibitor SGC0946 · an experimental structure of the same protein · chain A against A, TM-score 0.21
• 4ER6 · Crystal structure of human DOT1L in complex with inhibitor SGC0946 · an experimental structure of the same protein · chain A against A, TM-score 0.21
• 6NJ9 · Active state DOT1L bound to the H2B-ubiquitinated nucleosome, 2-to-1 complex · an experimental structure of the same protein · chain A against M, TM-score 0.21
• 6NJ9 · Active state Dot1L bound to the H2B-Ubiquitinated nucleosome, 2-to-1 complex · an experimental structure of the same protein · chain A against M, TM-score 0.21
• 3SR4 · Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.21
• 3SR4 · Crystal structure of human DOT1L in complex with a selective inhibitor · an experimental structure of the same protein · chain A against A, TM-score 0.21
• 1NW3 · Structure of the catalytic domain of human DOT1L, a non-set domain nucleosomal histone… · an experimental structure of the same protein · chain A against A, TM-score 0.21

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q8TEK3
• Elsewhere: UniProt Q8TEK3 · AlphaFold DB Q8TEK3