UniProt W5PUX0
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (W5PUX0)
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (UniProt W5PUX0), EC 1.6.99.3, 7.1.1.2: 59 experimental structures on GenesisL1, 4 ligands bound, 23 pockets. Binding sites, pockets, druggability and 3D structures in…
- UniProt
- W5PUX0
- Protein
- NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial
- EC
- 1.6.99.3, 7.1.1.2
- Experimental structures
- 59
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 23 · 5 records with a druggable one
Structures
59 records of W5PUX0 in the MolNFT archive: 59 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LNK | Entire ovine respiratory complex I | electron microscopy | 1 | SF4, FMN, FES | — |
| 5LNK | Entire ovine respiratory complex I | electron microscopy | 1 | SF4, FMN, FES | — |
| 6Q9D | CI Peripheral Arm focused refinement from Ovine respiratory SC I+III2 | electron microscopy | V1 | SF4, FMN, FES | 6 (best 0.78) |
| 6QA9 | Isolated complex I class refinement from Ovine respiratory supercomplex I+III2 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QBX | Ovine respiratory supercomplex I+III2 closed class. | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC2 | Ovine respiratory supercomplex I+III2 open class 2 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC3 | Ovine respiratory supercomplex I+III2 open class 1 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC4 | Ovine respiratory supercomplex I+III2 open class 3 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC5 | Ovine respiratory complex I FRC closed class 1 | electron microscopy | V1 | SF4, FMN | — |
| 6QC6 | Ovine respiratory complex I FRC open class 1 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC7 | Ovine respiratory complex I FRC open class 3 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC8 | Ovine respiratory complex I FRC open class 2 | electron microscopy | V1 | SF4, FMN, FES | — |
| 6QC9 | Ovine respiratory complex I FRC open class 4 | electron microscopy | V1 | SF4, FMN, FES | 5 (best 0.85) |
| 6QCA | Ovine respiratory complex I FRC open class 5 | electron microscopy | V1 | SF4, FMN, FES | 4 (best 0.79) |
| 6QCF | Ovine respiratory complex I FRC open class 6 | electron microscopy | V1 | SF4, FMN, FES | 3 (best 0.79) |
| 6ZK9 | Peripheral domain of open complex I during turnover | electron microscopy | 1 | SF4, FMN, NAI, FES | 5 (best 0.78) |
| 6ZK9 | Peripheral domain of open complex I during turnover | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKC | Complex I during turnover, closed | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKC | Complex I during turnover, closed | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKD | Complex I during turnover, open1 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKD | Complex I during turnover, OPEN1 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKE | Complex I during turnover, open2 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKE | Complex I during turnover, OPEN2 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKF | Complex I during turnover, open3 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKF | Complex I during turnover, OPEN3 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKG | Complex I with NADH, closed | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKG | Complex I with NADH, closed | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKH | Complex I with NADH, open1 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKH | Complex I with NADH, OPEN1 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKI | Complex I with NADH, open2 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKI | Complex I with NADH, OPEN2 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKJ | Complex I with NADH, open3 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKJ | Complex I with NADH, OPEN3 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKK | Complex I inhibited by rote , closed | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKK | Complex I inhibited by rotenone, closed | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKL | Complex I inhibited by rote , open1 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKL | Complex I inhibited by rotenone, OPEN1 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKM | Complex I inhibited by rotenone, OPEN2 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKN | Complex I inhibited by rote , open3 | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 6ZKN | Complex I inhibited by rotenone, OPEN3 | electron microscopy | 1 | SF4, FMN, NAI | — |
| 6ZKO | Native complex I, closed | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKO | Native complex I, closed | electron microscopy | 1 | SF4, FMN | — |
| 6ZKP | Native complex I, open1 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKP | Native complex I, OPEN1 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKQ | Native complex I, open2 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKQ | Native complex I, OPEN2 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKR | Native complex I, open3 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKR | Native complex I, OPEN3 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKS | Deactive complex I, open1 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKS | Deactive complex I, OPEN1 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKT | Deactive complex I, open2 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKT | Deactive complex I, OPEN2 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKU | Deactive complex I, open3 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKU | Deactive complex I, OPEN3 | electron microscopy | 1 | SF4, FMN | — |
| 6ZKV | Deactive complex I, open4 | electron microscopy | 1 | SF4, FMN, FES | — |
| 6ZKV | Deactive complex I, OPEN4 | electron microscopy | 1 | SF4, FMN | — |
| 7ZD6 | Complex I from Ovis aries, at pH7.4, Open state | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 7ZDH | Complex I from Ovis aries at pH7.4, Closed state | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
| 7ZDM | Complex I from Ovis aries at pH5.5, Closed state | electron microscopy | 1 | SF4, FMN, NAI, FES | — |
Ligands
Elsewhere
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