UniProt V7II86
Threonine--tRNA ligase (V7II86)
Threonine--tRNA ligase (UniProt V7II86), EC 6.1.1.3: 13 experimental structures on GenesisL1, 8 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- V7II86
- Protein
- Threonine--tRNA ligase
- EC
- 6.1.1.3
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 11 · 2 records with a druggable one
Structures
13 records of V7II86 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6L2P | Threonyl-tRNA synthetase from Salmonella enterica in the apo form | x-ray diffraction | A, B | ZN | — |
| 6L2P | Threonyl-tRNA synthetase from salmonella enterica in the apo form | x-ray diffraction | A, B | ZN | — |
| 6L2Q | Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | ZN, E4O | — |
| 6L2Q | Threonyl-tRNA synthetase from salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | ZN, E4O | — |
| 7CBG | Crystal structure of threonyl-tRNA synthetase (thrrs) from salmonella enterica in complex with an… | x-ray diffraction | A, B | FQL, ZN | — |
| 7CBH | Crystal structure of threonyl-tRNA synthetase (thrrs) from salmonella enterica in complex with an… | x-ray diffraction | A, B | FQR, ZN | — |
| 7CBI | Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an… | x-ray diffraction | A, B | ZN, FQU | — |
| 7CBI | Crystal structure of threonyl-tRNA synthetase (thrrs) from salmonella enterica in complex with an… | x-ray diffraction | A, B | ZN, FQU | — |
| 7WM7 | Threonyl-tRNA synthetase from salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | ZN, 9I6 | — |
| 7WMF | Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | 9I9, ZN | 6 (best 0.80) |
| 7WMF | Threonyl-tRNA synthetase from salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | 9I9, ZN | — |
| 7WMI | Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | ZN, 9IC | 5 (best 0.81) |
| 7WMI | Threonyl-tRNA synthetase from salmonella enterica in complex with an inhibitor | x-ray diffraction | A, B | ZN, 9IC | — |
Ligands
- ZN · Zinc ion · in 13 records
- 9I9 · (2S,3R)-2-azanyl-N-[(1R)-2-[3-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]propanoylamino]-1-[3-[4-(trifluoromethyl)phenyl]phenyl]ethyl]-3-oxidanyl-butanamide · in 2 records
- 9IC · (2S,3R)-2-azanyl-N-[(1R)-2-[3-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)propanoylamino]-1-(3-phenylphenyl)ethyl]-3-oxidanyl-butanamide · in 2 records
- E4O · (2S,3R)-2-azanyl-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-3-oxidanyl-butanamide · in 2 records
- FQU · 5-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)pentyl (2~{S},3~{R})-2-azanyl-3-oxidanyl-butanoate · in 2 records
- 9I6 · (2S,3R)-2-azanyl-N-[5-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)pentyl]-3-oxidanyl-N-[[3-(1-oxidanylidene-2,3-dihydroisoindol-5-yl) phenyl]methyl]butanamide · in 1 record
- FQL · (2S,3R)-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-2-(methylamino)-3-oxidanyl-butanamide · in 1 record
- FQR · [(E)-4-(7-bromanyl-6-chloranyl-4-oxidanylidene-quinazolin-3-yl)but-2-enyl] (2S,3R)-2-azanyl-3-oxidanyl-butanoate · in 1 record
Elsewhere
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