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UniProt U3GU88

RNA-dependent RNA-polymerase L protein (U3GU88)

RNA-dependent RNA-polymerase L protein (UniProt U3GU88), EC 2.7.7.48: 8 experimental structures on GenesisL1, 2 ligands bound, 160 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
U3GU88
Protein
RNA-dependent RNA-polymerase L protein
EC
2.7.7.48
Experimental structures
8
Predicted models
0
Ligands
2
Pockets
160 · 8 records with a druggable one

Structures

8 records of U3GU88 in the MolNFT archive: 8 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8AS6Structure of the SFTSV L protein bound to 5' cRNA hook [5' HOOK]electron microscopyA—20 (best 0.81)
8AS7Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION]electron microscopyAMG, 2KH20 (best 0.84)
8ASBStructure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a…electron microscopyAMG, 2KH20 (best 0.87)
8ASDStructure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION]electron microscopyAMG, 2KH20 (best 0.84)
8ASGStructure of the SFTSV L protein bound in a resting state [RESTING]electron microscopyAMG20 (best 0.77)
8R6UStructure of the SFTSV L protein in a transcription-priming state without capped RNA…electron microscopyAMG20 (best 0.84)
8R6WStructure of the SFTSV L protein in a transcription-priming state with bound capped RNA…electron microscopyA—20 (best 0.86)
8R6YStructure of the SFTSV L protein stalled in a transcription-specific early elongation state with…electron microscopyA2KH, MG20 (best 0.85)

Ligands

  • MG · Magnesium ion · in 6 records
  • 2KH · 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine · in 4 records

Elsewhere

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