UniProt S4UY05
HCV NS3/4A protease (S4UY05)
HCV NS3/4A protease (UniProt S4UY05): 4 experimental structures on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- S4UY05
- Protein
- HCV NS3/4A protease
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 2 · 0 records with a druggable one
Structures
4 records of S4UY05 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NZT | Crystal structure of HCV NS3/4A protease in complex with voxilaprevir | x-ray diffraction | A | L9P, ZN, SO4 | 2 (best 0.39) |
| 6NZT | Crystal structure of HCV NS3/4A protease in complex with voxilaprevir | x-ray diffraction | A | L9P, ZN, SO4 | — |
| 6NZV | Crystal structure of HCV NS3/4A protease in complex with compound 12 | x-ray diffraction | A | L9J, ZN, SO4 | — |
| 6NZV | Crystal structure of HCV NS3/4A protease in complex with compound 12 | x-ray diffraction | A | L9J, ZN, SO4 | — |
Ligands
- SO4 · Sulfate ion · in 4 records
- ZN · Zinc ion · in 4 records
- L9J · (1ar,5s,8s,9s,10r,22ar)-5-tert-butyl-N-[(1R,2R)-2-(difluoromethyl)-1-{[(1-methylcyclopropyl) sulfonyl]carbamoyl}cyclopropyl]-9-ethyl-14-methoxy-3, 6-dioxo-1,1A,3,4,5,6,9,10,18,19,20,21,22,22A-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10, 3,6]dioxadiazacyclononadecino[11,12-b]quinoxaline-8-carboxamide · in 2 records
- L9P · Voxilaprevir · in 2 records
Elsewhere
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