UniProt R9THT8
RNA-dependent RNA polymerase (R9THT8)
RNA-dependent RNA polymerase (UniProt R9THT8), EC 2.7.7.48: 4 experimental structures on GenesisL1, 4 ligands bound, 12 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- R9THT8
- Protein
- RNA-dependent RNA polymerase
- EC
- 2.7.7.48
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 12 · 2 records with a druggable one
Structures
4 records of R9THT8 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5QJ0 | CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 NS5B RNA-DEPENDENT RNA… | x-ray diffraction | A | J6D, SCN | 5 (best 0.84) |
| 5QJ0 | Crystal structure of the hepatitis C virus genotype 2A strain JFH1 NS5B RNA-dependent RNA… | x-ray diffraction | A | J6D, SCN | — |
| 5QJ1 | CRYSTAL STRUCTURE OF THE HEPATITIS C VIRUS GENOTYPE 2A STRAIN JFH1 L30S NS5B RNA-DEPENDENT RNA… | x-ray diffraction | A | J6J, SO4 | 7 (best 0.80) |
| 5QJ1 | Crystal structure of the hepatitis C virus genotype 2A strain JFH1 L30S NS5B RNA-dependent RNA… | x-ray diffraction | A | J6J, SO4 | — |
Ligands
- J6D · 6-[ethyl(methylsulfonyl)amino]-2-(4-fluorophenyl)-N-methyl-5-(3-{[1-(pyrimidin-2-yl) cyclopropyl]carbamoyl}phenyl)-1-benzofuran-3-carboxamide · in 2 records
- J6J · 6-(ethylamino)-2-(4-fluorophenyl)-5-(3-{[1-(5-fluoropyrimidin-2-yl)cyclopropyl]carbamoyl}-4-methoxyphenyl)-N-methyl-1-benzofuran-3-carboxamide · in 2 records
- SCN · Thiocyanate ion · in 2 records
- SO4 · Sulfate ion · in 2 records
Elsewhere
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