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UniProt R9TEU1

Genome polyprotein (R9TEU1)

Genome polyprotein (UniProt R9TEU1): 4 experimental structures on GenesisL1, 5 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
R9TEU1
Protein
Genome polyprotein
Experimental structures
4
Predicted models
0
Ligands
5
Pockets
9 · 2 records with a druggable one

Structures

4 records of R9TEU1 in the MolNFT archive: 4 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5UJ2Crystal structure of HCV NS5B genotype 2A JFH-1 isolate with S15G E86Q E87Q C223H V321I mutations…x-ray diffractionAMN, 8B4, CL4 (best 0.77)
5UJ2Crystal structure of HCV NS5B genotype 2A jfh-1 isolate with S15G E86Q E87Q C223H V321I mutations…x-ray diffractionAMN, CL—
5WDXStructure of NS3 from HCV strain JFH-1 that is an unusually robust helicase that is primed to bind…x-ray diffractionAZN, MG5 (best 0.79)
5WDXStructure of NS3 from HCV strain jfh-1 that is an unusually robust helicase that is primed to bind…x-ray diffractionAZN, MG—

Ligands

  • CL · Chloride ion · in 2 records
  • MG · Magnesium ion · in 2 records
  • MN · Manganese (II) ion · in 2 records
  • ZN · Zinc ion · in 2 records
  • 8B4 · (1S)-1-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)-1,4-anhydro-2-deoxy-2-fluoro-5-O-[(S)-hydroxy(phosphonooxy)phosphoryl]-2-methyl-D-ribitol · in 1 record

Elsewhere

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