UniProt Q9ZMY2
Aminodeoxyfutalosine nucleosidase (Q9ZMY2)
Aminodeoxyfutalosine nucleosidase (UniProt Q9ZMY2), EC 3.2.2.30, 3.2.2.9: 34 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9ZMY2
- Protein
- Aminodeoxyfutalosine nucleosidase
- EC
- 3.2.2.30, 3.2.2.9
- Experimental structures
- 34
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 4 · 4 records with a druggable one
Structures
35 records of Q9ZMY2 in the MolNFT archive: 34 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3NM4 | Helicobacter pylori MTAN | x-ray diffraction | A, B | — | — |
| 3NM4 | Helicobacter pylori mtan | x-ray diffraction | A, B | — | — |
| 3NM5 | Helicobacter pylori MTAN complexed with Formycin A | x-ray diffraction | A, B | — | — |
| 3NM5 | Helicobacter pylori mtan complexed with formycin a | x-ray diffraction | A, B | — | — |
| 3NM6 | Helicobacter pylori MTAN complexed with adenine and tris | x-ray diffraction | B | — | — |
| 3NM6 | Helicobacter pylori mtan complexed with adenine and tris | x-ray diffraction | B | — | — |
| 4FFS | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Helicobacter… | x-ray diffraction | A | — | — |
| 4FFS | Crystal structure of 5'-METHYLTHIOADENOSINE/S-adenosylhomocysteine nucleosidase from helicobacter… | x-ray diffraction | A | — | — |
| 4OJT | Helicobacter pylori MTAN complexed with S-ribosylhomocysteine and adenine | x-ray diffraction | A | — | — |
| 4OJT | Helicobacter pylori mtan complexed with S-ribosylhomocysteine and adenine | x-ray diffraction | A | — | — |
| 4OY3 | Crystal Structure of the Helicobacter pylori MTAN-D198N mutant with S-Adenosylhomocysteine in the… | x-ray diffraction | A | — | — |
| 4OY3 | Crystal structure of the helicobacter pylori mtan-D198N mutant with S- adenosylhomocysteine in the… | x-ray diffraction | A | — | — |
| 4P54 | Crystal Structure of the Helicobacter pylori MTAN-D198N mutant with 5'-methylthioadenosine in the… | x-ray diffraction | A | — | — |
| 4P54 | Crystal structure of the helicobacter pylori mtan-D198N mutant with 5'-methylthioadenosine in the… | x-ray diffraction | A | — | — |
| 4WKN | Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4WKN | Crystal structure of helicobacter pylori 5'-METHYLTHIOADENOSINE/S- adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4WKO | Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4WKO | Crystal structure of helicobacter pylori 5'-METHYLTHIOADENOSINE/S- adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4WKP | Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine… | x-ray diffraction | A, B, C, D | — | — |
| 4WKP | Crystal structure of helicobacter pylori 5'-METHYLTHIOADENOSINE/S- adenosyl homocysteine… | x-ray diffraction | A, B, C, D | — | — |
| 4YNB | Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4YNB | Crystal structure of helicobacter pylori 5'-METHYLTHIOADENOSINE/S- adenosyl homocysteine… | x-ray diffraction | A | — | — |
| 4YO8 | Crystal structure of Helicobacter pylori 5'-methylthioadenosine/S-adenosyl homocysteine… | x-ray diffraction | A, B | — | — |
| 4YO8 | Crystal structure of helicobacter pylori 5'-METHYLTHIOADENOSINE/S- adenosyl homocysteine… | x-ray diffraction | A, B | — | — |
| 5CCD | Joint X-ray/neutron structure of MTAN D198N complex with SAH | x-ray diffraction, neutron diffraction | A | SAH | 1 (best 0.61) |
| 5CCD | Joint X-RAY/NEUTRON structure of mtan D198N complex with sah | x-ray diffraction; neutron diffraction | A | — | — |
| 5CCE | Joint X-ray/neutron structure of wild type MTAN complexed with SRH and adenine | neutron diffraction, x-ray diffraction | A | 2WP, ADE | 1 (best 0.61) |
| 5CCE | Joint X-RAY/NEUTRON structure of wild type mtan complexed with srh and adenine | neutron diffraction; x-ray diffraction | A | — | — |
| 5JPC | Joint X-ray/neutron structure of MTAN complex with Formycin A | neutron diffraction, x-ray diffraction | A | FMC | — |
| 5JPC | Joint X-RAY/NEUTRON structure of mtan complex with formycin a | neutron diffraction; x-ray diffraction | A | — | — |
| 5K1Z | Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA | neutron diffraction, x-ray diffraction | A | 4CT | 1 (best 0.61) |
| 5K1Z | Joint X-RAY/NEUTRON structure of mtan complex with P-clph-thio-dadme- imma | neutron diffraction; x-ray diffraction | A | 4CT | — |
| 5KB3 | 1.4 A resolution structure of Helicobacter Pylori MTAN in complexed with p-ClPh-DADMe-ImmA | x-ray diffraction | A | 4CT, MG | — |
| 5KB3 | 1.4 a resolution structure of helicobacter pylori mtan in complexed with P-clph-dadme-imma | x-ray diffraction | A | 4CT, MG | — |
| Q9ZMY2 | AlphaFold monomer V2.0 prediction for aminodeoxyfutalosine nucleosidase (Q9ZMY2) | predicted | A | — | 1 (best 0.63) |
Ligands
- 4CT · (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl) methyl]-4-{[(4-chlorophenyl) sulfanyl]methyl}pyrrolidin-3-ol · in 4 records
- MG · Magnesium ion · in 2 records
- 2WP · S-ribosylhomocysteine · in 1 record
- ADE · Adenine · in 1 record
- FMC · (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol · in 1 record
- SAH · S-adenosyl-L-homocysteine · in 1 record
Experiment against prediction
- 3NM6 chain B against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.21 Å
- 3NM6 chain B against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.21 Å
- 4OJT chain A against the predicted model Q9ZMY2: TM-score 0.99, RMSD 0.23 Å
- 4OJT chain A against the predicted model Q9ZMY2: TM-score 0.99, RMSD 0.23 Å
- 4P54 chain A against the predicted model Q9ZMY2: TM-score 0.99, RMSD 0.23 Å
- 4P54 chain A against the predicted model Q9ZMY2: TM-score 0.99, RMSD 0.23 Å
- 4YNB chain A against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.23 Å
- 4YNB chain A against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.23 Å
- 4WKO chain A against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.23 Å
- 4WKO chain A against the predicted model Q9ZMY2: TM-score 1.00, RMSD 0.23 Å
Elsewhere
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