UniProt Q9Z1W9
STE20/SPS1-related proline-alanine-rich protein kinase (Q9Z1W9)
STE20/SPS1-related proline-alanine-rich protein kinase (UniProt Q9Z1W9): 2 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Z1W9
- Protein
- STE20/SPS1-related proline-alanine-rich protein kinase
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of Q9Z1W9 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5D9H | Crystal structure of spak (STK39) dimer in the basal activity state | x-ray diffraction | A, B | — | — |
| 5DBX | Crystal structure of murine SPAK(T243D) in complex with amppnp | x-ray diffraction | A, B | — | — |
| Q9Z1W9 | AlphaFold monomer V2.0 prediction for STE20/SPS1-related proline- alanine-rich protein kinase… | predicted | A | — | 5 (best 0.78) |
Experiment against prediction
- 5D9H chain A against the predicted model Q9Z1W9: TM-score 0.93, RMSD 1.48 Å
- 5D9H chain B against the predicted model Q9Z1W9: TM-score 0.92, RMSD 1.55 Å
- 5DBX chain B against the predicted model Q9Z1W9: TM-score 0.91, RMSD 1.88 Å
- 5DBX chain A against the predicted model Q9Z1W9: TM-score 0.91, RMSD 1.86 Å
Elsewhere
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