UniProt Q9YUI7
Integrase (Q9YUI7)
Integrase (UniProt Q9YUI7): 2 experimental structures on GenesisL1, 5 ligands bound, 25 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q9YUI7
- Protein
- Integrase
- Experimental structures
- 2
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 25 · 1 record with a druggable one
Structures
2 records of Q9YUI7 in the MolNFT archive: 2 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7UE1 | HIV-1 Integrase Catalytic Core Domain Mutant (KGD) in Complex with Inhibitor GRL-142 | x-ray diffraction | A, B | 7OA, SO4 | 5 (best 0.46) |
| 8W09 | HIV-1 wild-type intasome core | electron microscopy | A, B, C, D, I, K, L, M | MG, ZN, DLU | 20 (best 0.77) |
Ligands
- 7OA · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl [(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-1-(3,5-difluorophenyl)-3-hydroxybutan-2-yl]carbamate · in 1 record
- DLU · (4r,12as)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6, 8-dioxo-3,4,6,8,12,12A-hexahydro-2H-pyrido[1',2':4, 5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide · in 1 record
- MG · Magnesium ion · in 1 record
- SO4 · Sulfate ion · in 1 record
- ZN · Zinc ion · in 1 record
Elsewhere
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