UniProt Q9YGN6
Single-strand selective monofunctional uracil DNA glycosylase (Q9YGN6)
Single-strand selective monofunctional uracil DNA glycosylase (UniProt Q9YGN6), EC 3.2.2.-: 6 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 19 pockets. Binding sites, druggability and experiment…
- UniProt
- Q9YGN6
- Protein
- Single-strand selective monofunctional uracil DNA glycosylase
- EC
- 3.2.2.-
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 19 · 4 records with a druggable one
Structures
7 records of Q9YGN6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1OE4 | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | x-ray diffraction | A, B | — | 6 (best 0.73) |
| 1OE4 | Xenopus SMUG1, an anti-mutator uracil-DNA glycosylase | x-ray diffraction | A, B | — | — |
| 1OE5 | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | x-ray diffraction | A, B | URA | 5 (best 0.75) |
| 1OE5 | Xenopus SMUG1, an anti-mutator uracil-DNA glycosylase | x-ray diffraction | A, B | — | — |
| 1OE6 | Xenopus SMUG1, an anti-mutator uracil-DNA Glycosylase | x-ray diffraction | A, B | HMU | 6 (best 0.73) |
| 1OE6 | Xenopus SMUG1, an anti-mutator uracil-DNA glycosylase | x-ray diffraction | A, B | — | — |
| Q9YGN6 | AlphaFold monomer V2.0 prediction for single-strand selective monofunctional uracil DNA glycosylase… | predicted | A | — | 2 (best 0.57) |
Ligands
Experiment against prediction
- 1OE5 chain B against the predicted model Q9YGN6: TM-score 1.00, RMSD 0.25 Å
- 1OE5 chain B against the predicted model Q9YGN6: TM-score 1.00, RMSD 0.25 Å
- 1OE6 chain B against the predicted model Q9YGN6: TM-score 1.00, RMSD 0.26 Å
- 1OE6 chain B against the predicted model Q9YGN6: TM-score 1.00, RMSD 0.26 Å
- 1OE4 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.42 Å
- 1OE4 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.42 Å
- 1OE6 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.46 Å
- 1OE6 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.46 Å
- 1OE5 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.47 Å
- 1OE5 chain A against the predicted model Q9YGN6: TM-score 0.99, RMSD 0.47 Å
Elsewhere
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