UniProt Q9Y6Y9
Lymphocyte antigen 96 (Q9Y6Y9)
Lymphocyte antigen 96 (UniProt Q9Y6Y9): 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y6Y9
- Protein
- Lymphocyte antigen 96
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 2 · 2 records with a druggable one
Structures
13 records of Q9Y6Y9 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E56 | Crystal structure of human MD-2 | x-ray diffraction | A | NAG, MYR | 1 (best 0.77) |
| 2E56 | Crystal structure of human md-2 | x-ray diffraction | A | — | — |
| 2E59 | Crystal structure of human MD-2 in complex with lipid IVa | x-ray diffraction | A | NAG, LP5, LP4 | 1 (best 0.77) |
| 2E59 | Crystal structure of human md-2 in complex with lipid iva | x-ray diffraction | A | — | — |
| 2Z65 | Crystal structure of the human TLR4 TV3 hybrid-MD-2-Eritoran complex | x-ray diffraction | C, D | — | — |
| 2Z65 | Crystal structure of the human TLR4 TV3 hybrid-md-2-eritoran complex | x-ray diffraction | C, D | — | — |
| 3FXI | Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex | x-ray diffraction | C, D | — | — |
| 3FXI | Crystal structure of the human TLR4-human md-2-E.COLI lps ra complex | x-ray diffraction | C, D | — | — |
| 3ULA | Crystal structure of the TV3 mutant F63W-MD-2-Eritoran complex | x-ray diffraction | B, D | — | — |
| 3ULA | Crystal structure of the TV3 mutant F63W-md-2-eritoran complex | x-ray diffraction | B, D | — | — |
| 4G8A | Crystal structure of human TLR4 polymorphic variant D299G and T399I in complex with MD-2 and LPS | x-ray diffraction | C, D | — | — |
| 4G8A | Crystal structure of human TLR4 polymorphic variant D299G and T399I in complex with md-2 and lps | x-ray diffraction | C, D | — | — |
| Q9Y6Y9 | AlphaFold monomer V2.0 prediction for lymphocyte antigen 96 (Q9Y6Y9) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
- LP4 · 2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-4-O-phosphono-beta-D-glucopyranose · in 1 record
- LP5 · (R)-((2R,3S,4R,5R,6R)-3-hydroxy-2-(hydroxymethyl)-5-((R)-3-hydroxytetradecanamido)-6-(phosphonooxy) tetrahydro-2H-pyran-4-yl) 3-hydroxytetradecanoate · in 1 record
- MYR · Myristic acid · in 1 record
Experiment against prediction
- 3FXI chain C against the predicted model Q9Y6Y9: TM-score 0.97, RMSD 0.89 Å
- 3FXI chain C against the predicted model Q9Y6Y9: TM-score 0.97, RMSD 0.89 Å
- 4G8A chain C against the predicted model Q9Y6Y9: TM-score 0.97, RMSD 0.89 Å
- 4G8A chain C against the predicted model Q9Y6Y9: TM-score 0.97, RMSD 0.89 Å
- 3ULA chain B against the predicted model Q9Y6Y9: TM-score 0.96, RMSD 1.20 Å
- 3ULA chain B against the predicted model Q9Y6Y9: TM-score 0.96, RMSD 1.20 Å
- 2Z65 chain C against the predicted model Q9Y6Y9: TM-score 0.96, RMSD 1.18 Å
- 2Z65 chain C against the predicted model Q9Y6Y9: TM-score 0.96, RMSD 1.18 Å
- 2E59 chain A against the predicted model Q9Y6Y9: TM-score 0.95, RMSD 1.13 Å
- 2E59 chain A against the predicted model Q9Y6Y9: TM-score 0.95, RMSD 1.13 Å
Elsewhere
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