UniProt Q9Y6W8
Inducible T-cell costimulator (Q9Y6W8)
Inducible T-cell costimulator (UniProt Q9Y6W8): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y6W8
- Protein
- Inducible T-cell costimulator
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of Q9Y6W8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6X4G | Crystal structure of ICOS in complex with ICOS-L and an anti ICOS-L VNAR domain | x-ray diffraction | A | NAG | 1 (best 0.40) |
| 6X4G | Crystal structure of icos in complex with icos-L and an anti icos-L vnar domain | x-ray diffraction | A | NAG | — |
| 7JOO | Crystal structure of ICOS in complex with antibody STIM003 and anti-kappa VHH domain | x-ray diffraction | C | NAG | — |
| 7JOO | Crystal structure of icos in complex with antibody STIM003 and anti- kappa vhh domain | x-ray diffraction | C | NAG | — |
| Q9Y6W8 | AlphaFold monomer V2.0 prediction for inducible T-cell costimulator (Q9Y6W8) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 4 records
Experiment against prediction
- 6X4G chain A against the predicted model Q9Y6W8: TM-score 0.85, RMSD 1.65 Å
- 6X4G chain A against the predicted model Q9Y6W8: TM-score 0.85, RMSD 1.65 Å
- 7JOO chain C against the predicted model Q9Y6W8: TM-score 0.84, RMSD 1.91 Å
- 7JOO chain C against the predicted model Q9Y6W8: TM-score 0.84, RMSD 1.91 Å
Elsewhere
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