UniProt Q9Y6Q9
Nuclear receptor coactivator 3 (Q9Y6Q9)
Nuclear receptor coactivator 3 (UniProt Q9Y6Q9), EC 2.3.1.48: 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9Y6Q9
- Protein
- Nuclear receptor coactivator 3
- EC
- 2.3.1.48
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 5 · 0 records with a druggable one
Structures
10 records of Q9Y6Q9 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KBH | Mutual Synergistic Folding in the Interaction Between Nuclear Receptor Coactivators CBP and ACTR | solution nmr | A | — | — |
| 1KBH | Mutual synergistic folding in the interaction between nuclear receptor coactivators cbp and actr | solution nmr | A | — | — |
| 3L3X | Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid… | x-ray diffraction | B | — | — |
| 3L3X | Crystal structure of dht-bound androgen receptor in complex with the first motif of steroid… | x-ray diffraction | B | — | — |
| 3L3Z | Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid… | x-ray diffraction | B | — | — |
| 3L3Z | Crystal structure of dht-bound androgen receptor in complex with the third motif of steroid… | x-ray diffraction | B | — | — |
| 6ES7 | Structure and dynamics conspire in the evolution of affinity between intrinsically disordered… | solution nmr | A | — | — |
| 6SQC | Crystal structure of complex between nuclear coactivator binding domain of CBP and [1040-1086]ACTR… | x-ray diffraction | B | ZN | 1 (best 0.43) |
| 6SQC | Crystal structure of complex between nuclear coactivator binding domain of cbp and [1040-1086]ACTR… | x-ray diffraction | B | ZN | — |
| Q9Y6Q9 | AlphaFold monomer V2.0 prediction for nuclear receptor coactivator 3 (Q9Y6Q9) | predicted | A | — | 4 (best 0.50) |
Ligands
- ZN · Zinc ion · in 2 records
Experiment against prediction
- 3L3Z chain B against the predicted model Q9Y6Q9: TM-score 0.72, RMSD 1.58 Å
- 3L3Z chain B against the predicted model Q9Y6Q9: TM-score 0.72, RMSD 1.58 Å
- 3L3X chain B against the predicted model Q9Y6Q9: TM-score 0.56, RMSD 0.97 Å
- 3L3X chain B against the predicted model Q9Y6Q9: TM-score 0.56, RMSD 0.97 Å
- 6SQC chain B against the predicted model Q9Y6Q9: TM-score 0.51, RMSD 3.12 Å
- 6SQC chain B against the predicted model Q9Y6Q9: TM-score 0.51, RMSD 3.12 Å
- 1KBH chain A against the predicted model Q9Y6Q9: TM-score 0.40, RMSD 3.08 Å
- 1KBH chain A against the predicted model Q9Y6Q9: TM-score 0.40, RMSD 3.08 Å
- 6ES7 chain A against the predicted model Q9Y6Q9: TM-score 0.34, RMSD 3.38 Å
Elsewhere
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