UniProt Q9Y6D6
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (Q9Y6D6)
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (UniProt Q9Y6D6): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9Y6D6
- Protein
- Brefeldin A-inhibited guanine nucleotide-exchange protein 1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 7 · 2 records with a druggable one
Structures
7 records of Q9Y6D6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3LTL | Crystal structure of human BIG1 Sec7 domain | x-ray diffraction | A, B | — | — |
| 3LTL | Crystal structure of human BIG1 SEC7 domain | x-ray diffraction | A, B | — | — |
| 5EE5 | Structure of human ARL1 in complex with the DCB domain of BIG1 | x-ray diffraction | A | NA, CL | 3 (best 0.62) |
| 5EE5 | Structure of human ARL1 in complex with the dcb domain of BIG1 | x-ray diffraction | A | — | — |
| 5J5C | Crystal structure of ARL1-GTP and DCB domain of BIG1 complex | x-ray diffraction | B | SO4 | 4 (best 0.71) |
| 5J5C | Crystal structure of ARL1-GTP and dcb domain of BIG1 complex | x-ray diffraction | B | — | — |
| Q9Y6D6 | AlphaFold monomer V2.0 prediction for brefeldin a-inhibited guanine nucleotide-exchange protein 1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 5EE5 chain A against the predicted model Q9Y6D6: TM-score 0.96, RMSD 1.19 Å
- 5EE5 chain A against the predicted model Q9Y6D6: TM-score 0.96, RMSD 1.19 Å
- 3LTL chain A against the predicted model Q9Y6D6: TM-score 0.95, RMSD 1.46 Å
- 3LTL chain A against the predicted model Q9Y6D6: TM-score 0.95, RMSD 1.46 Å
- 3LTL chain B against the predicted model Q9Y6D6: TM-score 0.94, RMSD 1.39 Å
- 3LTL chain B against the predicted model Q9Y6D6: TM-score 0.94, RMSD 1.39 Å
- 5J5C chain B against the predicted model Q9Y6D6: TM-score 0.91, RMSD 1.92 Å
- 5J5C chain B against the predicted model Q9Y6D6: TM-score 0.91, RMSD 1.92 Å
Elsewhere
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