UniProt Q9Y698

Q9Y698

Q9Y698 (UniProt Q9Y698): 5 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9Y698
Experimental structures: 5
Predicted models: 1
Ligands: 3

Structures

6 records of Q9Y698 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6DLZ	Open state GLUA2 in complex with stz after micelle signal subtraction	electron microscopy	A, B, C, D	CYZ	—
6DM0	Open state GLUA2 in complex with stz and blocked by iem-1460, after micelle signal subtraction	electron microscopy	A, B, C, D	CYZ, GZD	—
6DM1	Open state GluA2 in complex with STZ and blocked by NASPM, after micelle signal subtraction	electron microscopy	A, B, C, D	CYZ, GYY	—
6DM1	Open state GLUA2 in complex with stz and blocked by naspm, after micelle signal subtraction	electron microscopy	A, B, C, D	CYZ, GYY	—
6O9G	Open state GLUA2 in complex with stz and blocked by agtx-636, after micelle signal subtraction	electron microscopy	A, B, C, D	CYZ	—
Q9Y698	AlphaFold monomer V2.0 prediction for voltage-dependent calcium channel gamma-2 subunit (Q9Y698)	predicted	A	—	—

Ligands

CYZ · Cyclothiazide · in 5 records
GYY · N-[3-({4-[(3-aminopropyl)amino]butyl}amino)propyl]-2-(naphthalen-1-yl)acetamide · in 2 records
GZD · N,N,N-trimethyl-5-({[(3S,5S,7S)-tricyclo[3.3.1.1~3, 7~]decan-1-yl]methyl}amino)pentan-1-aminium · in 1 record

Experiment against prediction

6O9G chain A against the predicted model P19491: TM-score 0.71, RMSD 3.93 Å
6O9G chain C against the predicted model P19491: TM-score 0.71, RMSD 3.93 Å
6DM1 chain C against the predicted model P19491: TM-score 0.71, RMSD 3.88 Å
6DM1 chain A against the predicted model P19491: TM-score 0.71, RMSD 3.84 Å
6O9G chain A against the predicted model Q9Y698: TM-score 0.19, RMSD 1.67 Å
6O9G chain C against the predicted model Q9Y698: TM-score 0.19, RMSD 1.67 Å
6DM0 chain A against the predicted model Q9Y698: TM-score 0.19, RMSD 1.69 Å
6O9G chain B against the predicted model Q9Y698: TM-score 0.19, RMSD 1.67 Å
6DM0 chain C against the predicted model Q9Y698: TM-score 0.19, RMSD 1.70 Å
6O9G chain D against the predicted model Q9Y698: TM-score 0.19, RMSD 1.67 Å

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.