UniProt Q9Y5Y0
Heme transporter FLVCR1 (Q9Y5Y0)
Heme transporter FLVCR1 (UniProt Q9Y5Y0): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5Y0
- Protein
- Heme transporter FLVCR1
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 12 · 8 records with a druggable one
Structures
9 records of Q9Y5Y0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8QCS | Cryo-EM structure of the inward-facing FLVCR1 | electron microscopy | A | — | 1 (best 0.78) |
| 8QCT | Cryo-EM structure of the inward-facing choline-bound FLVCR1 | electron microscopy | A | CHT | 3 (best 0.73) |
| 8R8T | Cryo-EM structure of the inward-facing ethanolamine-bound FLVCR1 | electron microscopy | A | ETA | 1 (best 0.78) |
| 8UBW | Choline-bound FLVCR1 | electron microscopy | A | Y01, CHT | 2 (best 0.77) |
| 8UBX | Ethanolamine-bound FLVCR1 | electron microscopy | A | ETA, Y01 | 1 (best 0.78) |
| 8UBY | Choline-bound FLVCR1 | electron microscopy | A | Y01, CHT | 1 (best 0.79) |
| 8UBZ | Choline-bound FLVCR1 | electron microscopy | A | Y01, CHT | 1 (best 0.79) |
| 8UC0 | Endogenous ligand bound FLVCR1 | electron microscopy | A | Y01 | 2 (best 0.77) |
| Q9Y5Y0 | AlphaFold monomer V2.0 prediction for feline leukemia virus subgroup C receptor-related protein 1… | predicted | A | — | — |
Ligands
Experiment against prediction
- 8UBZ chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.53 Å
- 8QCT chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.75 Å
- 8UBW chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.63 Å
- 8R8T chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.76 Å
- 8UBX chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.67 Å
- 8QCS chain A against the predicted model Q9Y5Y0: TM-score 0.96, RMSD 1.72 Å
- 8UBY chain A against the predicted model Q9Y5Y0: TM-score 0.95, RMSD 1.84 Å
- 8UC0 chain A against the predicted model Q9Y5Y0: TM-score 0.94, RMSD 2.10 Å
Elsewhere
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