UniProt Q9Y5S9
RNA-binding protein 8A (Q9Y5S9)
RNA-binding protein 8A (UniProt Q9Y5S9): 28 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5S9
- Protein
- RNA-binding protein 8A
- Experimental structures
- 28
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
29 records of Q9Y5S9 in the MolNFT archive: 28 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1P27 | Crystal Structure of the Human Y14/Magoh complex | x-ray diffraction | B, D | — | — |
| 1P27 | Crystal structure of the human Y14/MAGOH complex | x-ray diffraction | B, D | — | — |
| 2HYI | Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA | x-ray diffraction | B, H | — | — |
| 2HYI | Structure of the human exon junction complex with a trapped dead-box helicase bound to RNA | x-ray diffraction | B, H | — | — |
| 2J0Q | The crystal structure of the Exon Junction Complex at 3.2 A resolution | x-ray diffraction | D, G | — | — |
| 2J0Q | The crystal structure of the exon junction complex at 3.2 a resolution | x-ray diffraction | D, G | — | — |
| 2J0S | The crystal structure of the Exon Junction Complex at 2.2 A resolution | x-ray diffraction | D | — | — |
| 2J0S | The crystal structure of the exon junction complex at 2.2 a resolution | x-ray diffraction | D | — | — |
| 2XB2 | Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is… | x-ray diffraction | D, Z | — | — |
| 2XB2 | Crystal structure of the core mago-Y14-EIF4AIII-barentsz- UPF3B assembly shows how the ejc is… | x-ray diffraction | D, Z | — | — |
| 3EX7 | The crystal structure of EJC in its transition state | x-ray diffraction | B, G | — | — |
| 3EX7 | The crystal structure of ejc in its transition state | x-ray diffraction | B, G | — | — |
| 5XJC | Cryo-EM structure of the human spliceosome just prior to exon ligation at 3.6 angstrom | electron microscopy | w | — | — |
| 5YZG | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | electron microscopy | w | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom | electron microscopy | w | — | — |
| 6ICZ | Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 ångström | electron microscopy | w | — | — |
| 6QDV | Human post-catalytic P complex spliceosome | electron microscopy | 8 | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | w | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | w | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | w | — | — |
| 7W59 | The cryo-EM structure of human pre-C*-I complex | electron microscopy | w | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | w | — | — |
| 7W5A | The cryo-EM structure of human pre-C*-II complex | electron microscopy | w | — | — |
| 7W5B | The cryo-EM structure of human C* complex | electron microscopy | w | — | — |
| 7ZNJ | Structure of an ALYREF-exon junction complex hexamer | electron microscopy | C, c, H, h, M, m | — | 7 (best 0.81) |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | 8 | — | 1 (best 0.84) |
| 8I0W | The cryo-EM structure of human C complex | electron microscopy | w | — | — |
| 9FMD | Integrative model of the human post-catalytic spliceosome (P-complex) | electron microscopy | 8 | — | — |
| Q9Y5S9 | AlphaFold monomer V2.0 prediction for RNA-binding protein 8A (Q9Y5S9) | predicted | A | — | 1 (best 0.36) |
Experiment against prediction
- 3EX7 chain B against the predicted model Q9Y5S9: TM-score 1.00, RMSD 0.23 Å
- 3EX7 chain B against the predicted model Q9Y5S9: TM-score 1.00, RMSD 0.23 Å
- 7A5P chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 7A5P chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 7W5B chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 7W59 chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 7W59 chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 2HYI chain B against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 2HYI chain B against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
- 7W5A chain w against the predicted model Q9Y5S9: TM-score 0.99, RMSD 0.25 Å
Elsewhere
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