UniProt Q9Y5A7
Isoform 2 of NEDD8 ultimate buster 1 (Q9Y5A7)
Isoform 2 of NEDD8 ultimate buster 1 (UniProt Q9Y5A7): 10 experimental structures and 1 predicted model on GenesisL1, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y5A7
- Protein
- Isoform 2 of NEDD8 ultimate buster 1
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 15 · 2 records with a druggable one
Structures
11 records of Q9Y5A7 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1WJU | Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1 | solution nmr | A | — | — |
| 1WJU | Solution structure of N-terminal ubiquitin-like domain of human NEDD8 ultimate buster-1 | solution nmr | A | — | — |
| 8USB | Non-substrate-engaged human 26S proteasome with Nub1/FAT10 bound to Rpn1 | electron microscopy | g | — | — |
| 8USC | Nub1/Fat10-processing human 26S proteasome | electron microscopy | g | — | — |
| 8USD | Rpn1/Nub1UBL-focused alignment of the non-substrate-engaged human 26S proteasome | electron microscopy | g | — | 3 (best 0.58) |
| 9E8H | Human proteasome in resting state conformation bound to TXNL1 in backward conformation | electron microscopy | g | — | — |
| 9E8I | Human proteasome in resting state conformation bound to TXNL1 in Forward conformation | electron microscopy | g | — | — |
| 9E8J | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt1 at top of spiral staircase | electron microscopy | g | — | — |
| 9E8L | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt4 at top of spiral staircase | electron microscopy | g | — | — |
| 9E8N | Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase | electron microscopy | g | — | — |
| Q9Y5A7 | AlphaFold monomer V2.0 prediction for NEDD8 ultimate buster 1 (Q9Y5A7) | predicted | A | — | 12 (best 0.75) |
Experiment against prediction
- 8USB chain g against the predicted model Q9Y5A7: TM-score 0.87, RMSD 1.96 Å
- 9E8I chain g against the predicted model Q9Y5A7: TM-score 0.86, RMSD 1.98 Å
- 9E8H chain g against the predicted model Q9Y5A7: TM-score 0.86, RMSD 2.12 Å
- 9E8L chain g against the predicted model Q9Y5A7: TM-score 0.85, RMSD 2.29 Å
- 8USD chain g against the predicted model Q9Y5A7: TM-score 0.85, RMSD 2.32 Å
- 8USC chain g against the predicted model Q9Y5A7: TM-score 0.84, RMSD 2.32 Å
- 9E8N chain g against the predicted model Q9Y5A7: TM-score 0.83, RMSD 2.25 Å
- 1WJU chain A against the predicted model Q9Y5A7: TM-score 0.75, RMSD 1.76 Å
- 1WJU chain A against the predicted model Q9Y5A7: TM-score 0.75, RMSD 1.76 Å
- 9E8J chain g against the predicted model Q9Y5A7: TM-score 0.68, RMSD 3.18 Å
Elsewhere
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