UniProt Q9Y570
Protein phosphatase methylesterase 1 (Q9Y570)
Protein phosphatase methylesterase 1 (UniProt Q9Y570), EC 3.1.1.89: 6 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y570
- Protein
- Protein phosphatase methylesterase 1
- EC
- 3.1.1.89
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 6 · 2 records with a druggable one
Structures
7 records of Q9Y570 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3C5V | PP2A-specific methylesterase apo form (PME) | x-ray diffraction | A | — | — |
| 3C5V | PP2A-specific methylesterase apo form (pme) | x-ray diffraction | A | — | — |
| 3C5W | Complex between PP2A-specific methylesterase PME-1 and PP2A core enzyme | x-ray diffraction | P | — | — |
| 3C5W | Complex between PP2A-specific methylesterase pme-1 and PP2A core enzyme | x-ray diffraction | P | — | — |
| 7SOY | The structure of the PP2A-B56gamma1 holoenzyme-PME-1 complex | electron microscopy | P | — | 4 (best 0.75) |
| 7SOY | The structure of the PP2A-B56GAMMA1 holoenzyme-pme-1 complex | electron microscopy | P | — | — |
| Q9Y570 | AlphaFold monomer V2.0 prediction for protein phosphatase methylesterase 1 (Q9Y570) | predicted | A | — | 2 (best 0.74) |
Experiment against prediction
- 3C5W chain P against the predicted model Q9Y570: TM-score 0.99, RMSD 0.62 Å
- 3C5W chain P against the predicted model Q9Y570: TM-score 0.99, RMSD 0.62 Å
- 3C5V chain A against the predicted model Q9Y570: TM-score 0.98, RMSD 0.96 Å
- 3C5V chain A against the predicted model Q9Y570: TM-score 0.98, RMSD 0.96 Å
- 7SOY chain P against the predicted model Q9Y570: TM-score 0.94, RMSD 1.36 Å
- 7SOY chain P against the predicted model Q9Y570: TM-score 0.94, RMSD 1.36 Å
Elsewhere
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