UniProt Q9Y4U1
Methylmalonic aciduria and homocystinuria type C protein (Q9Y4U1)
Methylmalonic aciduria and homocystinuria type C protein (UniProt Q9Y4U1), EC 1.16.1.-: 10 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 1 pocket. Binding sites, druggability and experiment against…
- UniProt
- Q9Y4U1
- Protein
- Methylmalonic aciduria and homocystinuria type C protein
- EC
- 1.16.1.-
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 1 · 1 record with a druggable one
Structures
11 records of Q9Y4U1 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3SBY | Crystal Structure of SeMet-Substituted Apo-MMACHC (1-244), a human B12 processing enzyme | x-ray diffraction | A, B | — | — |
| 3SBY | Crystal structure of semet-substituted apo-mmachc (1-244), a human B12 processing enzyme | x-ray diffraction | A, B | — | — |
| 3SBZ | Crystal Structure of Apo-MMACHC (1-244), a human B12 processing enzyme | x-ray diffraction | A | — | — |
| 3SBZ | Crystal structure of apo-mmachc (1-244), a human B12 processing enzyme | x-ray diffraction | A | — | — |
| 3SC0 | Crystal Structure of MMACHC (1-238), a human B12 processing enzyme, complexed with MethylCobalamin | x-ray diffraction | A | — | — |
| 3SC0 | Crystal structure of mmachc (1-238), a human B12 processing enzyme, complexed with methylcobalamin | x-ray diffraction | A | — | — |
| 3SOM | crystal structure of human MMACHC | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 3SOM | Crystal structure of human mmachc | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P | — | — |
| 5UOS | Crystal Structure of CblC (MMACHC) (1-238), a human B12 processing enzyme, complexed with an… | x-ray diffraction | A | B12, GSH, 171, SO4 | 1 (best 0.58) |
| 5UOS | Crystal structure of cblc (mmachc) (1-238), a human B12 processing enzyme, complexed with an… | x-ray diffraction | A | B12, GSH, 171, SO4 | — |
| Q9Y4U1 | AlphaFold monomer V2.0 prediction for cyanocobalamin reductase / alkylcobalamin dealkylase (Q9Y4U1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 3SOM chain P against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.50 Å
- 3SOM chain P against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.50 Å
- 3SOM chain A against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.50 Å
- 3SOM chain A against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.50 Å
- 3SOM chain C against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.51 Å
- 3SOM chain C against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.51 Å
- 3SOM chain B against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.52 Å
- 3SOM chain B against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.52 Å
- 3SOM chain E against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.53 Å
- 3SOM chain E against the predicted model Q9Y4U1: TM-score 0.99, RMSD 0.53 Å
Elsewhere
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