UniProt Q9Y4G2
Pleckstrin homology domain-containing family M member 1 (Q9Y4G2)
Pleckstrin homology domain-containing family M member 1 (UniProt Q9Y4G2): 9 experimental structures and 1 predicted model on GenesisL1, 40 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y4G2
- Protein
- Pleckstrin homology domain-containing family M member 1
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 40 · 4 records with a druggable one
Structures
10 records of Q9Y4G2 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DPR | Crystal structure of PLEKHM1 LIR-fused human LC3A_2-121 | x-ray diffraction | A, B, C, D | — | 8 (best 0.48) |
| 5DPR | Crystal structure of PLEKHM1 lir-fused human LC3A_2-121 | x-ray diffraction | A, B, C, D | — | — |
| 5DPS | Crystal structure of PLEKHM1 LIR-fused human GABARAP_2-117 | x-ray diffraction | A, B, C | — | 5 (best 0.51) |
| 5DPS | Crystal structure of PLEKHM1 lir-fused human GABARAP_2-117 | x-ray diffraction | A, B, C | — | — |
| 5DPT | Crystal structure of PLEKHM1 LIR-fused human GABARAPL1_2-117 | x-ray diffraction | A, B | — | 5 (best 0.53) |
| 5DPT | Crystal structure of PLEKHM1 lir-fused human GABARAPL1_2-117 | x-ray diffraction | A, B | — | — |
| 5DPW | Crystal structure of PLEKHM1 LIR in complex with human LC3C_8-125 | x-ray diffraction | B, D, F, H, J, L, N, P | — | 4 (best 0.49) |
| 5DPW | Crystal structure of PLEKHM1 lir in complex with human LC3C_8-125 | x-ray diffraction | B, D, F, H, J, L, N, P | — | — |
| 8JC5 | Crystal structure of PLEKHM1 RUN domain in complex with GTP-bound Arl8b(Q75L) | x-ray diffraction | C, D | — | 10 (best 0.75) |
| Q9Y4G2 | AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family M member 1… | predicted | A | — | 8 (best 0.74) |
Experiment against prediction
- 5DPS chain A against the predicted model O95166: TM-score 0.93, RMSD 0.57 Å
- 5DPS chain A against the predicted model O95166: TM-score 0.93, RMSD 0.57 Å
- 5DPS chain C against the predicted model O95166: TM-score 0.93, RMSD 0.47 Å
- 5DPS chain C against the predicted model O95166: TM-score 0.93, RMSD 0.47 Å
- 5DPT chain A against the predicted model Q9H0R8: TM-score 0.92, RMSD 0.56 Å
- 5DPT chain A against the predicted model Q9H0R8: TM-score 0.92, RMSD 0.56 Å
- 5DPS chain B against the predicted model O95166: TM-score 0.91, RMSD 0.69 Å
- 5DPS chain B against the predicted model O95166: TM-score 0.91, RMSD 0.69 Å
- 5DPR chain B against the predicted model Q9H492: TM-score 0.90, RMSD 1.13 Å
- 5DPR chain B against the predicted model Q9H492: TM-score 0.90, RMSD 1.13 Å
Elsewhere
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