UniProt Q9Y3Y4
Pygopus homolog 1 (Q9Y3Y4)
Pygopus homolog 1 (UniProt Q9Y3Y4): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3Y4
- Protein
- Pygopus homolog 1
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 15 · 3 records with a druggable one
Structures
11 records of Q9Y3Y4 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VP7 | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | A | SO4, ZN | — |
| 2VP7 | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | A | SO4, ZN | — |
| 2VPB | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | A | NA, ZN | — |
| 2VPB | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | A | NA, ZN | — |
| 2VPD | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | A, C | ZN | 1 (best 0.66) |
| 2VPD | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | A, C | ZN | 1 (best 0.66) |
| 2VPE | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | A, C | ZN | 3 (best 0.40) |
| 2VPE | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | A, C | ZN | 3 (best 0.40) |
| 2VPG | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | A, C | ZN | 3 (best 0.43) |
| 2VPG | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | A, C | ZN | 3 (best 0.43) |
| Q9Y3Y4 | AlphaFold monomer V2.0 prediction for pygopus homolog 1 (Q9Y3Y4) | predicted | A | — | 1 (best 0.52) |
Ligands
Experiment against prediction
- 2VPB chain A against the predicted model Q9Y3Y4: TM-score 0.97, RMSD 0.46 Å
- 2VPB chain A against the predicted model Q9Y3Y4: TM-score 0.97, RMSD 0.46 Å
- 2VPG chain C against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.82 Å
- 2VPG chain C against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.82 Å
- 2VPD chain A against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.61 Å
- 2VPD chain A against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.61 Å
- 2VPE chain C against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.86 Å
- 2VPE chain C against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 0.86 Å
- 2VPE chain A against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 1.01 Å
- 2VPE chain A against the predicted model Q9Y3Y4: TM-score 0.95, RMSD 1.01 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.