UniProt Q9Y3D6
Mitochondrial fission 1 protein (Q9Y3D6)
Mitochondrial fission 1 protein (UniProt Q9Y3D6): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3D6
- Protein
- Mitochondrial fission 1 protein
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 12 · 2 records with a druggable one
Structures
9 records of Q9Y3D6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1NZN | Cytosolic domain of the human mitchondrial fission protein Fis1 adopts a TPR fold | x-ray diffraction | A | — | — |
| 1NZN | Cytosolic domain of the human mitchondrial fission protein FIS1 adopts a tpr fold | x-ray diffraction | A | — | — |
| 1PC2 | Solution structure of human mitochondria fission protein Fis1 | solution nmr | A | — | — |
| 1PC2 | Solution structure of human mitochondria fission protein FIS1 | solution nmr | A | — | — |
| 7YA9 | Fis1 (Mitochondrial fission 1 protein) | x-ray diffraction | A | NA | — |
| 7YKA | Crystal structure of Fis1 (Mitochondrial fission 1 protein) | x-ray diffraction | A, B | ZN | 3 (best 0.64) |
| 8U1Z | Crystal structure of the Fis1 cytosolic domain bound to a peptide inhibitor | x-ray diffraction | A | — | 2 (best 0.33) |
| 8XWX | Crystal structure of FIS1-BAP31 complex from human | x-ray diffraction | A, C, B | SO4 | 7 (best 0.62) |
| Q9Y3D6 | AlphaFold monomer V2.0 prediction for mitochondrial fission 1 protein (Q9Y3D6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7YA9 chain A against the predicted model Q9Y3D6: TM-score 0.94, RMSD 0.99 Å
- 8U1Z chain A against the predicted model Q9Y3D6: TM-score 0.93, RMSD 1.81 Å
- 7YKA chain B against the predicted model Q9Y3D6: TM-score 0.93, RMSD 0.95 Å
- 8XWX chain B against the predicted model Q9Y3D6: TM-score 0.93, RMSD 1.09 Å
- 7YKA chain A against the predicted model Q9Y3D6: TM-score 0.92, RMSD 1.10 Å
- 8XWX chain A against the predicted model Q9Y3D6: TM-score 0.92, RMSD 1.01 Å
- 8XWX chain C against the predicted model Q9Y3D6: TM-score 0.92, RMSD 1.13 Å
- 1NZN chain A against the predicted model Q9Y3D6: TM-score 0.90, RMSD 1.70 Å
- 1NZN chain A against the predicted model Q9Y3D6: TM-score 0.90, RMSD 1.70 Å
- 1PC2 chain A against the predicted model Q9Y3D6: TM-score 0.74, RMSD 2.68 Å
Elsewhere
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