UniProt Q9Y3C7
Mediator of RNA polymerase II transcription subunit 31 (Q9Y3C7)
Mediator of RNA polymerase II transcription subunit 31 (UniProt Q9Y3C7): 7 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y3C7
- Protein
- Mediator of RNA polymerase II transcription subunit 31
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
8 records of Q9Y3C7 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7EMF | Human Mediator (deletion of MED1-IDR) in a Tail-extended conformation | electron microscopy | 4 | — | 1 (best 0.74) |
| 7EMF | Human mediator (deletion of MED1-idr) in a tail-extended conformation | electron microscopy | 4 | — | — |
| 7ENA | TFIID-based PIC-Mediator holo-complex in pre-assembled state (pre-hPIC-MED) | electron microscopy | m | — | — |
| 7ENC | TFIID-based PIC-Mediator holo-complex in fully-assembled state (hPIC-MED) | electron microscopy | m | — | — |
| 7ENJ | Human mediator (deletion of MED1-idr) in a tail-bent conformation (med-B) | electron microscopy | 4 | — | — |
| 7NVR | Human Mediator with RNA Polymerase II Pre-initiation complex | electron microscopy | o | — | — |
| 7NVR | Human mediator with RNA polymerase II pre-initiation complex | electron microscopy | o | — | — |
| Q9Y3C7 | AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 31… | predicted | A | — | — |
Experiment against prediction
- 7NVR chain o against the predicted model Q9Y3C7: TM-score 0.94, RMSD 0.91 Å
- 7NVR chain o against the predicted model Q9Y3C7: TM-score 0.94, RMSD 0.91 Å
- 7ENJ chain 4 against the predicted model Q9Y3C7: TM-score 0.85, RMSD 1.60 Å
- 7EMF chain 4 against the predicted model Q9Y3C7: TM-score 0.85, RMSD 1.60 Å
- 7EMF chain 4 against the predicted model Q9Y3C7: TM-score 0.85, RMSD 1.60 Å
- 7ENC chain m against the predicted model Q9Y3C7: TM-score 0.84, RMSD 1.56 Å
- 7ENA chain m against the predicted model Q9Y3C7: TM-score 0.84, RMSD 1.56 Å
Elsewhere
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