UniProt Q9Y333
U6 snRNA-associated Sm-like protein LSm2 (Q9Y333)
U6 snRNA-associated Sm-like protein LSm2 (UniProt Q9Y333): 22 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y333
- Protein
- U6 snRNA-associated Sm-like protein LSm2
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 8 · 8 records with a druggable one
Structures
23 records of Q9Y333 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JCR | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | electron microscopy | 2 | — | — |
| 3JCR | 3D structure determination of the HUMAN*U4/U6.U5* tri-snrnp complex | electron microscopy | 2 | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | o | — | — |
| 5O9Z | Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) | electron microscopy | o | — | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | q | — | 1 (best 0.73) |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | q | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | q | — | — |
| 6QW6 | Structure of the human U5.U4/U6 tri-snRNP at 2.9A resolution. | electron microscopy | 62 | — | — |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | 62 | — | — |
| 7ABG | Human pre-Bact-1 spliceosome | electron microscopy | V | — | 1 (best 0.79) |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 6a | — | — |
| 8H6J | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | electron microscopy | 6a | — | — |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 6a | — | — |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 6a | — | — |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | 62 | — | — |
| 8QXD | Cryo-EM structure of the cross-exon pre-B complex | electron microscopy | 62 | — | 1 (best 0.85) |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | 62 | — | — |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | 62 | — | 1 (best 0.82) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | 62 | — | 1 (best 0.85) |
| 8R0A | Cryo-EM structure of the cross-exon pre-B+5'ss complex | electron microscopy | 62 | — | 1 (best 0.83) |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | 62 | — | 1 (best 0.86) |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | 62 | — | 1 (best 0.86) |
| Q9Y333 | AlphaFold monomer V2.0 prediction for U6 snrna-associated sm-like protein LSM2 (Q9Y333) | predicted | A | — | — |
Experiment against prediction
- 6QW6 chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 0.92 Å
- 6QX9 chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 0.92 Å
- 8R09 chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 0.98 Å
- 8R0A chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 1.00 Å
- 8R0B chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 1.00 Å
- 8RM5 chain 62 against the predicted model Q9Y333: TM-score 0.93, RMSD 1.00 Å
- 8QXD chain 62 against the predicted model Q9Y333: TM-score 0.92, RMSD 1.02 Å
- 8R08 chain 62 against the predicted model Q9Y333: TM-score 0.92, RMSD 1.05 Å
- 8QZS chain 62 against the predicted model Q9Y333: TM-score 0.90, RMSD 1.41 Å
- 8H6E chain 6a against the predicted model Q9Y333: TM-score 0.89, RMSD 1.49 Å
Elsewhere
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