UniProt Q9Y2U8
Inner nuclear membrane protein Man1 (Q9Y2U8)
Inner nuclear membrane protein Man1 (UniProt Q9Y2U8): 6 experimental structures and 1 predicted model on GenesisL1, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y2U8
- Protein
- Inner nuclear membrane protein Man1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
7 records of Q9Y2U8 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2CH0 | Solution structure of the human MAN1 C-terminal domain (residues 655- 775) | solution nmr | A | — | — |
| 2CH0 | Solution structure of the human MAN1 C-terminal domain (residues 655- 775) | solution nmr | A | — | — |
| 5ZOJ | Crystal structure of human SMAD2-MAN1 complex | x-ray diffraction | D, E | — | 3 (best 0.48) |
| 5ZOJ | Crystal structure of human SMAD2-MAN1 complex | x-ray diffraction | D, E | — | — |
| 5ZOK | Crystal structure of human SMAD1-MAN1 complex. | x-ray diffraction | B, D | — | 5 (best 0.72) |
| 5ZOK | Crystal structure of human SMAD1-MAN1 complex. | x-ray diffraction | B, D | — | — |
| Q9Y2U8 | AlphaFold monomer V2.0 prediction for inner nuclear membrane protein MAN1 (Q9Y2U8) | predicted | A | — | 5 (best 0.38) |
Experiment against prediction
- 5ZOK chain D against the predicted model Q9Y2U8: TM-score 0.99, RMSD 0.51 Å
- 5ZOK chain D against the predicted model Q9Y2U8: TM-score 0.99, RMSD 0.51 Å
- 5ZOJ chain D against the predicted model Q9Y2U8: TM-score 0.98, RMSD 0.54 Å
- 5ZOJ chain D against the predicted model Q9Y2U8: TM-score 0.98, RMSD 0.54 Å
- 5ZOJ chain E against the predicted model Q9Y2U8: TM-score 0.98, RMSD 0.61 Å
- 5ZOJ chain E against the predicted model Q9Y2U8: TM-score 0.98, RMSD 0.61 Å
- 5ZOK chain B against the predicted model Q9Y2U8: TM-score 0.95, RMSD 1.11 Å
- 5ZOK chain B against the predicted model Q9Y2U8: TM-score 0.95, RMSD 1.11 Å
- 2CH0 chain A against the predicted model Q9Y2U8: TM-score 0.50, RMSD 4.10 Å
- 2CH0 chain A against the predicted model Q9Y2U8: TM-score 0.50, RMSD 4.10 Å
Elsewhere
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