UniProt Q9Y2H2
Phosphatidylinositide phosphatase SAC2 (Q9Y2H2)
Phosphatidylinositide phosphatase SAC2 (UniProt Q9Y2H2), EC 3.1.3.-: 2 experimental structures and 1 predicted model on GenesisL1, 30 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y2H2
- Protein
- Phosphatidylinositide phosphatase SAC2
- EC
- 3.1.3.-
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 30 · 2 records with a druggable one
Structures
3 records of Q9Y2H2 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XUU | The hSac2 domain from human phosphoinositide phosphatase Sac2 | x-ray diffraction | A, B, C, D | — | 17 (best 0.76) |
| 4XUU | The HSAC2 domain from human phosphoinositide phosphatase SAC2 | x-ray diffraction | A, B, C, D | — | — |
| Q9Y2H2 | AlphaFold monomer V2.0 prediction for phosphatidylinositide phosphatase SAC2 (Q9Y2H2) | predicted | A | — | 13 (best 0.77) |
Experiment against prediction
- 4XUU chain A against the predicted model Q9Y2H2: TM-score 0.98, RMSD 1.16 Å
- 4XUU chain A against the predicted model Q9Y2H2: TM-score 0.98, RMSD 1.16 Å
- 4XUU chain B against the predicted model Q9Y2H2: TM-score 0.97, RMSD 1.08 Å
- 4XUU chain C against the predicted model Q9Y2H2: TM-score 0.97, RMSD 1.21 Å
- 4XUU chain C against the predicted model Q9Y2H2: TM-score 0.97, RMSD 1.21 Å
- 4XUU chain D against the predicted model Q9Y2H2: TM-score 0.95, RMSD 1.42 Å
Elsewhere
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