UniProt Q9Y262
Eukaryotic translation initiation factor 3 subunit L (Q9Y262)
Eukaryotic translation initiation factor 3 subunit L (UniProt Q9Y262): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y262
- Protein
- Eukaryotic translation initiation factor 3 subunit L
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
5 records of Q9Y262 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6YBD | Structure of a human 48S translational initiation complex - EIF3 | electron microscopy | 5 | — | — |
| 7A09 | Structure of a human ABCE1-bound 43S pre-initiation complex - State III | electron microscopy | L | — | — |
| 7QP6 | Structure of the human 48S initiation complex in open state (h48S AUG open) | electron microscopy | 5 | — | — |
| 8PPL | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | electron microscopy | I5 | — | 2 (best 0.86) |
| Q9Y262 | AlphaFold monomer V2.0 prediction for eukaryotic translation initiation factor 3 subunit L (Q9Y262) | predicted | A | — | — |
Experiment against prediction
- 8PPL chain I5 against the predicted model Q9Y262: TM-score 0.71, RMSD 3.93 Å
- 7A09 chain L against the predicted model Q9Y262: TM-score 0.71, RMSD 3.82 Å
- 6YBD chain 5 against the predicted model Q9Y262: TM-score 0.71, RMSD 4.18 Å
- 7QP6 chain 5 against the predicted model Q9Y262: TM-score 0.70, RMSD 4.38 Å
Elsewhere
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