UniProt Q9Y261
Hepatocyte nuclear factor 3-beta (Q9Y261)
Hepatocyte nuclear factor 3-beta (UniProt Q9Y261): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9Y261
- Protein
- Hepatocyte nuclear factor 3-beta
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 15 · 1 record with a druggable one
Structures
5 records of Q9Y261 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5X07 | Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site | x-ray diffraction | F, C, I, L | — | 11 (best 0.63) |
| 5X07 | Crystal structure of FOXA2 DNA binding domain bound to a full consensus DNA site | x-ray diffraction | F, C, I, L | — | — |
| 7YZE | Crystal structure of the human FoxA2 bound to the TGTTTACT site (forkhead motif GTAAACA) | x-ray diffraction | A | K, SO4 | 2 (best 0.36) |
| 7YZF | Crystal structure of the human FoxA2 bound to the TGTTTATT site (forkhead motif ATAAACA) | x-ray diffraction | C | K | 2 (best 0.33) |
| Q9Y261 | AlphaFold monomer V2.0 prediction for hepatocyte nuclear factor 3-beta (Q9Y261) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5X07 chain I against the predicted model Q9Y261: TM-score 0.97, RMSD 0.57 Å
- 5X07 chain I against the predicted model Q9Y261: TM-score 0.97, RMSD 0.57 Å
- 5X07 chain L against the predicted model Q9Y261: TM-score 0.95, RMSD 1.00 Å
- 5X07 chain L against the predicted model Q9Y261: TM-score 0.95, RMSD 1.00 Å
- 5X07 chain F against the predicted model Q9Y261: TM-score 0.95, RMSD 1.02 Å
- 5X07 chain F against the predicted model Q9Y261: TM-score 0.95, RMSD 1.02 Å
- 7YZF chain C against the predicted model Q9Y261: TM-score 0.93, RMSD 0.99 Å
- 7YZE chain A against the predicted model Q9Y261: TM-score 0.92, RMSD 1.00 Å
- 5X07 chain C against the predicted model Q9Y261: TM-score 0.91, RMSD 1.30 Å
- 5X07 chain C against the predicted model Q9Y261: TM-score 0.91, RMSD 1.30 Å
Elsewhere
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