UniProt Q9WTV6
Ubl carboxyl-terminal hydrolase 18 (Q9WTV6)
Ubl carboxyl-terminal hydrolase 18 (UniProt Q9WTV6), EC 3.4.19.-: 3 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q9WTV6
- Protein
- Ubl carboxyl-terminal hydrolase 18
- EC
- 3.4.19.-
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 2 records with a druggable one
Structures
4 records of Q9WTV6 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5CHT | Crystal structure of USP18 | x-ray diffraction | A, B | ZN | 8 (best 0.70) |
| 5CHT | Crystal structure of USP18 | x-ray diffraction | A, B | — | — |
| 5CHV | Crystal structure of USP18-ISG15 complex | x-ray diffraction | A, B | — | — |
| Q9WTV6 | AlphaFold monomer V2.0 prediction for ubl carboxyl-terminal hydrolase 18 (Q9WTV6) | predicted | A | — | 3 (best 0.53) |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 5CHV chain B against the predicted model Q9WTV6: TM-score 0.99, RMSD 0.76 Å
- 5CHV chain A against the predicted model Q9WTV6: TM-score 0.98, RMSD 0.89 Å
- 5CHT chain A against the predicted model Q9WTV6: TM-score 0.98, RMSD 1.22 Å
- 5CHT chain A against the predicted model Q9WTV6: TM-score 0.98, RMSD 1.22 Å
- 5CHT chain B against the predicted model Q9WTV6: TM-score 0.96, RMSD 1.42 Å
- 5CHT chain B against the predicted model Q9WTV6: TM-score 0.96, RMSD 1.42 Å
Elsewhere
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