UniProt Q9VZU4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (Q9VZU4)
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (UniProt Q9VZU4), EC 7.1.1.2: 4 experimental structures and 1 predicted model on GenesisL1, 19 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9VZU4
- Protein
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
- EC
- 7.1.1.2
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 19 · 4 records with a druggable one
Structures
5 records of Q9VZU4 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B9Z | Drosophila melanogaster complex I in the Active state (Dm1) | electron microscopy | C | — | 5 (best 0.88) |
| 8BA0 | Drosophila melanogaster complex I in the Twisted state (Dm2) | electron microscopy | C | — | 4 (best 0.90) |
| 8ESW | Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | electron microscopy | S3 | — | 3 (best 0.89) |
| 8ESZ | Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | electron microscopy | S3 | — | 5 (best 0.88) |
| Q9VZU4 | AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 3… | predicted | A | — | 2 (best 0.42) |
Experiment against prediction
- 8ESZ chain S3 against the predicted model Q9VZU4: TM-score 0.99, RMSD 0.65 Å
- 8ESW chain S3 against the predicted model Q9VZU4: TM-score 0.98, RMSD 0.80 Å
- 8B9Z chain C against the predicted model Q9VZU4: TM-score 0.98, RMSD 1.11 Å
- 8BA0 chain C against the predicted model Q9VZU4: TM-score 0.98, RMSD 1.08 Å
Elsewhere
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