UniProt Q9VUQ5
Argonaute 2 (Q9VUQ5)
Argonaute 2 (UniProt Q9VUQ5): 8 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9VUQ5
- Protein
- Argonaute 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
9 records of Q9VUQ5 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T2R | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | solution nmr | A | — | — |
| 1T2R | Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain | solution nmr | A | — | — |
| 1T2S | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | solution nmr | A | — | — |
| 1T2S | Structural basis for 3' end recognition of nucleic acids by the drosophila argonaute 2 paz domain | solution nmr | A | — | — |
| 1VYN | Structure and nucleic acid binding of the drosophila ARGONAUTE2 paz domain | solution nmr | A | — | 1 (best 0.42) |
| 1VYN | Structure and nucleic acid binding of the drosophila ARGONAUTE2 paz domain | solution nmr | A | — | — |
| 3MJ0 | Crystal Structure of Drosophia Ago-PAZ domain in complex with 3'-end 2'-O-methylated RNA | x-ray diffraction | A | — | — |
| 3MJ0 | Crystal structure of drosophia ago-paz domain in complex with 3'-end 2'-O-methylated RNA | x-ray diffraction | A | — | — |
| Q9VUQ5 | AlphaFold monomer V2.0 prediction for protein argonaute-2 (Q9VUQ5) | predicted | A | — | — |
Experiment against prediction
- 3MJ0 chain A against the predicted model Q9VUQ5: TM-score 0.93, RMSD 1.44 Å
- 3MJ0 chain A against the predicted model Q9VUQ5: TM-score 0.93, RMSD 1.44 Å
- 1VYN chain A against the predicted model Q9VUQ5: TM-score 0.88, RMSD 1.64 Å
- 1VYN chain A against the predicted model Q9VUQ5: TM-score 0.88, RMSD 1.64 Å
- 1T2R chain A against the predicted model Q9VUQ5: TM-score 0.87, RMSD 2.00 Å
- 1T2R chain A against the predicted model Q9VUQ5: TM-score 0.87, RMSD 2.00 Å
- 1T2S chain A against the predicted model Q9VUQ5: TM-score 0.84, RMSD 2.16 Å
- 1T2S chain A against the predicted model Q9VUQ5: TM-score 0.84, RMSD 2.16 Å
Elsewhere
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