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UniProt Q9UPY5

Cystine/glutamate transporter (Q9UPY5)

Cystine/glutamate transporter (UniProt Q9UPY5): 5 experimental structures on GenesisL1, 2 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q9UPY5
Protein
Cystine/glutamate transporter
Experimental structures
5
Predicted models
0
Ligands
2
Pockets
9 · 1 record with a druggable one

Structures

5 records of Q9UPY5 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7EPZOverall structure of Erastin-bound xCT-4F2hc complexelectron microscopyBJ9O, PX89 (best 0.74)
7EPZOverall structure of erastin-bound xct-4F2HC complexelectron microscopyBJ9O, PX8—
7P9UCryo EM structure of system xc- in complex with glutamateelectron microscopyB——
7P9VCryo EM structure of system xc-electron microscopyB——
Q9UPY5AlphaFold monomer V2.0 prediction for CYSTINE/GLUTAMATE transporter (Q9UPY5)———

Ligands

  • J9O · 2-[(1S)-1-[4-[2-(4-chloranylphenoxy)ethanoyl]piperazin-1-yl]ethyl]-3-(2-ethoxyphenyl)quinazolin-4-one · in 2 records
  • PX8 · 1,2-distearoyl-sn-glycero-3-phosphate · in 2 records

Elsewhere

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