UniProt Q9UPT6
C-Jun-amino-terminal kinase-interacting protein 3 (Q9UPT6)
C-Jun-amino-terminal kinase-interacting protein 3 (UniProt Q9UPT6): 5 experimental structures and 1 predicted model on GenesisL1, 22 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UPT6
- Protein
- C-Jun-amino-terminal kinase-interacting protein 3
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 22 · 4 records with a druggable one
Structures
6 records of Q9UPT6 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PXJ | Crystallographic structure of the LZII fragment (anti-parallel orientation) from JIP3 | x-ray diffraction | A, B, C | — | — |
| 4PXJ | Crystallographic structure of the lzii fragment (anti-parallel orientation) from JIP3 | x-ray diffraction | A, B, C | — | — |
| 8PR2 | Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI | electron microscopy | B, C | — | 4 (best 0.80) |
| 8PR3 | Cytoplasmic dynein-1 heavy chain bound to JIP3-RH1 | electron microscopy | B, C | — | 4 (best 0.77) |
| 8PR4 | Dynactin pointed end bound to JIP3 | electron microscopy | X, x | — | 3 (best 0.56) |
| Q9UPT6 | AlphaFold monomer V2.0 prediction for C-jun-amino-terminal kinase- interacting protein 3 (Q9UPT6) | predicted | A | — | 11 (best 0.83) |
Experiment against prediction
- 4PXJ chain B against the predicted model Q9UPT6: TM-score 0.90, RMSD 0.93 Å
- 4PXJ chain B against the predicted model Q9UPT6: TM-score 0.90, RMSD 0.93 Å
- 4PXJ chain A against the predicted model Q9UPT6: TM-score 0.89, RMSD 0.91 Å
- 4PXJ chain A against the predicted model Q9UPT6: TM-score 0.89, RMSD 0.91 Å
- 4PXJ chain C against the predicted model Q9UPT6: TM-score 0.87, RMSD 1.29 Å
- 4PXJ chain C against the predicted model Q9UPT6: TM-score 0.87, RMSD 1.29 Å
- 8PR3 chain B against the predicted model Q9UPT6: TM-score 0.83, RMSD 2.09 Å
- 8PR3 chain C against the predicted model Q9UPT6: TM-score 0.79, RMSD 2.18 Å
- 8PR2 chain B against the predicted model Q9UPT6: TM-score 0.74, RMSD 2.76 Å
- 8PR4 chain x against the predicted model Q9UPT6: TM-score 0.72, RMSD 2.58 Å
Elsewhere
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