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UniProt Q9UPI3

Heme transporter FLVCR2 (Q9UPI3)

Heme transporter FLVCR2 (UniProt Q9UPI3): 3 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q9UPI3
Protein
Heme transporter FLVCR2
Experimental structures
3
Predicted models
1
Ligands
2
Pockets
4 · 3 records with a druggable one

Structures

4 records of Q9UPI3 in the MolNFT archive: 3 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
8QCXCryo-EM structure of the inward-facing FLVCR2electron microscopyA—1 (best 0.78)
8QCZCryo-EM structure of the outward-facing heme-bound FLVCR2electron microscopyAHEM2 (best 0.73)
8QD0Cryo-EM structure of the inward-facing choline-bound FLVCR2electron microscopyACHT1 (best 0.78)
Q9UPI3AlphaFold monomer V2.0 prediction for feline leukemia virus subgroup C receptor-related protein 2…predictedA——

Ligands

  • CHT · Choline ion · in 1 record
  • HEM · Protoporphyrin IX containing Fe · in 1 record

Experiment against prediction

Elsewhere

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