UniProt Q9UP38
Frizzled-1 (Q9UP38)
Frizzled-1 (UniProt Q9UP38): 2 experimental structures and 1 predicted model on GenesisL1, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UP38
- Protein
- Frizzled-1
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 12 · 2 records with a druggable one
Structures
3 records of Q9UP38 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8J9N | Gq bound FZD1 in ligand-free state | electron microscopy | B | — | 5 (best 0.83) |
| 8J9O | Cryo-EM structure of inactive FZD1 | electron microscopy | A | — | 7 (best 0.81) |
| Q9UP38 | AlphaFold monomer V2.0 prediction for frizzled-1 (Q9UP38) | predicted | A | — | — |
Experiment against prediction
- 8J9N chain B against the predicted model Q9UP38: TM-score 0.95, RMSD 1.80 Å
- 8J9O chain A against the predicted model Q9UP38: TM-score 0.76, RMSD 1.68 Å
- 8J9O chain A against the predicted model P0ABE7: TM-score 0.22, RMSD 1.50 Å
Elsewhere
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