UniProt Q9UNU6
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (Q9UNU6)
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (UniProt Q9UNU6), EC 1.14.18.8: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 5 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q9UNU6
- Protein
- 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
- EC
- 1.14.18.8
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 5 · 1 record with a druggable one
Structures
3 records of Q9UNU6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7LYX | Crystal structure of human CYP8B1 in complex with (S)-tioconazole | x-ray diffraction | A | HEM, YHM, K | 5 (best 0.85) |
| 7LYX | Crystal structure of human CYP8B1 in complex with (S)-tioconazole | x-ray diffraction | A | HEM, YHM | — |
| Q9UNU6 | AlphaFold monomer V2.0 prediction for 7-alpha- hydroxycholest-4-en-3-one 12-alpha-hydroxylase… | predicted | A | — | — |
Ligands
Experiment against prediction
- 7LYX chain A against the predicted model Q9UNU6: TM-score 0.98, RMSD 1.16 Å
- 7LYX chain A against the predicted model Q9UNU6: TM-score 0.98, RMSD 1.16 Å
Elsewhere
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