UniProt Q9UNL4
Inhibitor of growth protein 4 (Q9UNL4)
Inhibitor of growth protein 4 (UniProt Q9UNL4): 10 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UNL4
- Protein
- Inhibitor of growth protein 4
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
11 records of Q9UNL4 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2K1J | Plan homeodomain finger of tumour supressor ING4 | solution nmr | A | — | — |
| 2K1J | Plan homeodomain finger of tumour supressor ING4 | solution nmr | A | — | — |
| 2M1R | PHD domain of ING4 N214D mutant | solution nmr | A | — | — |
| 2M1R | Phd domain of ING4 N214D mutant | solution nmr | A | — | — |
| 2PNX | The PHD finger of ING4 in complex with an H3K4Me3 histone peptide | x-ray diffraction | A, C | — | — |
| 2PNX | The phd finger of ING4 in complex with an H3K4ME3 histone peptide | x-ray diffraction | A, C | — | — |
| 2VNF | Molecular basis of histone H3K4ME3 recognition by ING4 | x-ray diffraction | A, C | — | — |
| 2VNF | Molecular basis of histone H3K4ME3 recognition by ING4 | x-ray diffraction | A, C | — | — |
| 4AFL | The crystal structure of the ING4 dimerization domain reveals the functional organization of the… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4AFL | The crystal structure of the ING4 dimerization domain reveals the functional organization of the… | x-ray diffraction | A, B, C, D, E, F | — | — |
| Q9UNL4 | AlphaFold monomer V2.0 prediction for inhibitor of growth protein 4 (Q9UNL4) | predicted | A | — | 1 (best 0.32) |
Experiment against prediction
- 2VNF chain A against the predicted model Q9UNL4: TM-score 0.97, RMSD 0.39 Å
- 2VNF chain A against the predicted model Q9UNL4: TM-score 0.97, RMSD 0.39 Å
- 2PNX chain C against the predicted model Q9UNL4: TM-score 0.95, RMSD 0.53 Å
- 2PNX chain C against the predicted model Q9UNL4: TM-score 0.95, RMSD 0.53 Å
- 2PNX chain A against the predicted model Q9UNL4: TM-score 0.95, RMSD 0.67 Å
- 2PNX chain A against the predicted model Q9UNL4: TM-score 0.95, RMSD 0.67 Å
- 2VNF chain C against the predicted model Q9UNL4: TM-score 0.91, RMSD 0.86 Å
- 2VNF chain C against the predicted model Q9UNL4: TM-score 0.91, RMSD 0.86 Å
- 4AFL chain F against the predicted model Q9UNL4: TM-score 0.90, RMSD 1.37 Å
- 4AFL chain F against the predicted model Q9UNL4: TM-score 0.90, RMSD 1.37 Å
Elsewhere
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