UniProt Q9ULR0
Pre-mRNA-splicing factor ISY1 homolog (Q9ULR0)
Pre-mRNA-splicing factor ISY1 homolog (UniProt Q9ULR0): 11 experimental structures and 1 predicted model on GenesisL1, 6 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9ULR0
- Protein
- Pre-mRNA-splicing factor ISY1 homolog
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 6 · 3 records with a druggable one
Structures
12 records of Q9ULR0 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5YZG | The Cryo-EM Structure of Human Catalytic Step I Spliceosome (C complex) at 4.1 angstrom resolution | electron microscopy | y | — | 3 (best 0.80) |
| 6FF7 | human Bact spliceosome core structure | electron microscopy | w | — | 1 (best 0.83) |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | w | — | — |
| 6ZYM | Human C Complex Spliceosome - High-resolution CORE | electron microscopy | s | — | 2 (best 0.82) |
| 6ZYM | Human C complex spliceosome - high-resolution core | electron microscopy | s | — | — |
| 7A5P | Human C Complex Spliceosome - Medium-resolution PERIPHERY | electron microscopy | s | — | — |
| 7A5P | Human C complex spliceosome - medium-resolution periphery | electron microscopy | s | — | — |
| 8C6J | Human spliceosomal PM5 C* complex | electron microscopy | CI | — | — |
| 8CH6 | Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius… | electron microscopy | t | — | — |
| 8RO2 | Integrative Structure of the human intron lariat Spliceosome (ILS'') | electron microscopy | D | — | — |
| 9FMD | Integrative model of the human post-catalytic spliceosome (P-complex) | electron microscopy | D | — | — |
| Q9ULR0 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ISY1 homolog (Q9ULR0) | predicted | A | — | — |
Experiment against prediction
- 6FF7 chain w against the predicted model Q9ULR0: TM-score 0.92, RMSD 0.74 Å
- 6FF7 chain w against the predicted model Q9ULR0: TM-score 0.92, RMSD 0.74 Å
- 8RO2 chain D against the predicted model Q9ULR0: TM-score 0.86, RMSD 0.98 Å
- 9FMD chain D against the predicted model Q9ULR0: TM-score 0.69, RMSD 1.94 Å
- 8CH6 chain t against the predicted model Q9ULR0: TM-score 0.64, RMSD 1.82 Å
- 7A5P chain s against the predicted model Q9ULR0: TM-score 0.63, RMSD 0.83 Å
- 7A5P chain s against the predicted model Q9ULR0: TM-score 0.63, RMSD 0.83 Å
- 5YZG chain y against the predicted model Q9ULR0: TM-score 0.60, RMSD 2.33 Å
- 6ZYM chain s against the predicted model Q9ULR0: TM-score 0.53, RMSD 1.39 Å
- 6ZYM chain s against the predicted model Q9ULR0: TM-score 0.53, RMSD 1.39 Å
Elsewhere
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